Cancer: Understanding the Difference Between Cure and Remission

Cancer affects millions of people worldwide, bringing with it uncertainty and an entirely new vocabulary to learn. Two words that can be particularly confusing for patients and their families are cure and remission. Although both describe positive outcomes following cancer treatment, they do not mean the same thing.

Understanding the difference can help patients better understand their prognosis, treatment goals, and the need for continued monitoring after treatment.

In cancer care, the word “cure” generally means that there are no signs of cancer and doctors believe the cancer is not expected to return. However, physicians often use the word cautiously because it can be difficult to know with absolute certainty that every cancer cell has been eliminated.

The likelihood of recurrence varies considerably depending on the type of cancer, its stage, biological characteristics, response to treatment, and many other factors. For some cancers, the chance of recurrence becomes extremely low after a certain number of years. For others, recurrence may remain possible much later. Because of this, there is no single amount of time after which every cancer patient can automatically be considered cured.

Remission, on the other hand, means that the signs and symptoms of cancer have decreased or disappeared following treatment.

Remission may be partial or complete. Partial remission means the cancer has responded to treatment and decreased significantly but remains detectable. Complete remission generally means there are no detectable signs of cancer using the tests currently available.

That distinction is important.

Complete remission does not necessarily mean cure.

Even when cancer cannot be detected through bloodwork, imaging, bone marrow testing, or other available methods, a very small number of cancer cells may remain in the body. These cells may never cause another problem, or they may eventually begin growing again and lead to relapse.

This is one reason patients usually continue regular medical follow-ups even after achieving complete remission. Depending on the cancer, monitoring may include physical examinations, laboratory testing, imaging, bone marrow testing, or other surveillance. The goal is to watch for changes and identify a recurrence or progression as early as possible.

For many patients, remission is an enormously important milestone. It may mean the end of intensive treatment, fewer medical appointments, improved physical health, and the opportunity to return to activities that were interrupted by cancer. Some people remain in remission for many years or even for the rest of their lives.

For others, cancer may return and require additional treatment.

Certain cancers also challenge the traditional distinction between remission and cure. Some cancers can behave more like chronic diseases, with patients experiencing long periods of remission followed by relapse and additional treatment. Advances in cancer therapy are allowing some people to live for many years with cancers that once had much poorer outcomes.

Ultimately, cure and remission are both positive words, but they describe different things.

Remission means the cancer has significantly decreased or is no longer detectable. Cure means the cancer is considered unlikely to return. Neither term should replace continued communication with a patient's healthcare team about individual risk, monitoring, and long-term care.

Perhaps most importantly, remission does not have to mean spending every day waiting for cancer to return. It can also mean returning to work, traveling, celebrating birthdays, spending time with family, making plans, and simply living ordinary life again.

Cancer may remain part of a person's medical history, but it does not have to remain at the center of every chapter that follows.

I can also make this specifically about multiple myeloma, where the distinction between remission, MRD negativity, long-term remission, functional cure, and traditional “cure” becomes especially interesting.

Valentine’s Day: A Celebration of Love Through the Centuries

Valentine’s Day, celebrated each year on February 14, has become a day devoted to love, affection, and connection. From handwritten cards and bouquets of roses to romantic dinners and simple expressions of appreciation, the traditions surrounding Valentine’s Day have changed considerably over the centuries. Yet the idea at its heart has remained remarkably consistent: taking the time to let the people in our lives know they are loved.

The history of Valentine’s Day is a mixture of fact, tradition, and legend. The holiday takes its name from St. Valentine, although historians believe there may have been more than one Christian martyr named Valentine associated with February 14.

One of the most familiar legends tells of a Roman priest named Valentine who lived during the reign of Emperor Claudius II in the third century. According to the story, Valentine secretly performed marriages despite an imperial prohibition and was eventually imprisoned and executed. Other legends tell different versions of his story, making it difficult to separate historical fact from centuries of storytelling.

The association between Valentine’s Day and romantic love developed more clearly during the Middle Ages. By the 14th and 15th centuries, romantic traditions had become increasingly connected with February 14, particularly in England and France. Courtly love, poetry, and written expressions of affection helped transform the day into an occasion for celebrating romance.

Handwritten valentines eventually became one of the holiday’s most recognizable traditions. Lovers and admirers exchanged notes expressing affection, devotion, and sometimes humor. By the 19th century, advances in printing and postal services made commercially produced Valentine’s Day cards increasingly popular. Elaborate cards decorated with lace, ribbons, flowers, and illustrations allowed people to express everything from passionate love to friendship and playful affection.

Flowers also became closely associated with Valentine’s Day. Red roses, long connected with romance and passion, eventually became one of the holiday’s most recognizable symbols. During the Victorian era, flowers were frequently used to communicate feelings, with different varieties and colors carrying symbolic meanings. A bouquet could sometimes say what a person was too shy to put into words.

Chocolate and other gifts eventually joined cards and flowers as traditional expressions of affection. Today, Valentine’s Day gifts range from candy and jewelry to handmade presents and deeply personal keepsakes. For many people, however, the value of the gift has little to do with its price. A favorite meal, a handwritten letter, a photograph, or something connected to a shared memory can carry far more meaning than an expensive present.

Modern Valentine’s Day celebrations have also shifted toward experiences. Couples may plan romantic dinners, concerts, weekend getaways, or quiet evenings at home. Some choose February 14 for proposals, weddings, or other significant moments in their relationships. Others ignore the commercial side of the holiday altogether and create traditions of their own.

Perhaps one of the most meaningful changes to Valentine’s Day is that it no longer has to belong exclusively to romantic couples.

Friends celebrate one another. Parents give valentines to their children. Children exchange cards with classmates. Families share special meals, and coworkers sometimes exchange small treats or messages of appreciation. For some people, Valentine’s Day has simply become another opportunity to recognize the people who make their lives better.

That broader definition of love may be especially important because not everyone experiences Valentine’s Day in the same way. For someone who has recently lost a spouse or partner, the day may bring grief instead of celebration. Someone going through a divorce or breakup may find the endless displays of romance difficult. Others may simply be single and perfectly content to spend February 14 like any other day.

There is no right way to celebrate Valentine’s Day.

Love exists in far more places than romantic relationships. It exists between parents and children, grandparents and grandchildren, siblings, lifelong friends, neighbors, caregivers, and even the people who quietly show up when life becomes difficult.

After centuries of changing customs, perhaps that is the tradition worth keeping.

Valentine’s Day does not have to be about elaborate gifts, expensive dinners, or perfect romantic gestures. It can simply be a reminder to tell someone they matter.

Send the card. Make the phone call. Buy the flowers—or pick them from your own backyard. Have dinner with someone you love. Check on the friend who might be spending the day alone. Tell your children you are proud of them. Hold someone's hand a little longer.

Because while Valentine’s Day comes only once a year, the people we love deserve to know it far more often than that.